Choosing the right diesel additive can help a Duramax engine run cleaner, improve cetane, and protect fuel systems. The following picks focus on cetane boost, injector cleaning, cold-weather performance, and post-combustion cleaning. Each product is selected for compatibility with modern diesel engines and Duramax-powered pickups. Read on to compare features, performance notes, and how to choose the best option for your truck.
| Product | Brand | Key Benefit |
|---|---|---|
| Everyday Diesel Treatment (16 oz) | Hot Shot’s Secret | Cetane boost, injector cleaning, fuel system protection |
| AR6500 Diesel Treatment (40 oz) | Archoil | Post-combustion cleaning, turbo/DPF protection, MPG boost |
| AR6500 Diesel Treatment (40 oz) Two Pack | Archoil | Treats up to 800 gallons, strong cetane boost |
| Everyday Diesel Treatment 32 oz | Hot Shot’s Secret | 6-in-1 formula, injector and fuel system cleaner |
| EDT+ Winter Defense (16 oz) | Hot Shot’s Secret | Anti-gel, lubricity, cetane boost, cold-start improvement |
Hot Shot’s Secret Everyday Diesel Treatment 6-in-1 (16 oz)

Hot Shot’s Secret Everyday Diesel Treatment (HSSEDT16ZS) provides a 6-in-1 diesel fuel additive solution. It includes diesel injector cleaning, a diesel fuel system cleaner, and cetane-boosting properties. The formula is designed to improve performance, support engine health, and help the engine run smoothly and efficiently. Features emphasize cleaner injectors, improved lubricity, and reduced maintenance costs over time.
Archoil AR6500 Diesel Treatment (40 oz)

Archoil AR6500 is a 40-ounce diesel treatment that covers up to 400 gallons per bottle. It is formulated to address issues with modern diesel fuels, aiming to restore performance and fuel economy. Notably, it is positioned as the only diesel treatment that can clean the post-combustion system, including the turbo and DPF, to prevent premature failure and reduce regeneration frequency.
Archoil AR6500 Diesel Treatment (40 oz) Two Pack

This two-pack option doubles the treating capacity to 800 gallons. It leverages Archoil’s combustion modifier technology and cetane boost to improve power and response. The product emphasizes compatibility with modern diesel fuels and supports full-system performance improvements, including cleaner post-combustion pathways.
Hot Shot’s Secret Everyday Diesel Treatment 32 oz

This 32-ounce EDT formula delivers the same 6-in-1 benefits as the smaller bottle, including injector cleaning, fuel system cleansing, and cetane enhancement. The larger volume is oriented toward regular maintenance on Duramax-powered trucks, supporting smoother starts, consistent performance, and reduced fuel-related wear when used as part of a routine fueling plan.
Hot Shot’s Secret EDT+ Winter Defense 16 oz

EDT+ Winter Defense combines 7-in-1 anti-gel protection with cetane boost, lubricity improvements, and water demulsification. It is designed for winter conditions, helping prevent gelling and ensuring reliable cold starts. For Duramax owners facing freezing temperatures, this product can reduce fuel line freeze-ups and protect the fuel system against rust and corrosion.
Hot Shot’s Secret EDT+ Winter Defense 8 oz

This compact 8-ounce EDT+ Winter Defense offers the same winter-first protection in a smaller bottle. It targets anti-gel performance, cetane boosting, lubricity, and moisture demulsification, making it a flexible option for owners who prefer to carry a lighter supply during cold-season commutes.
Archoil AR6300 Winter Diesel Treatment

Archoil AR6300 is a winter-rated diesel treatment with anti-gel protection. It includes cetane boosting and protection for fuel pumps and injectors. While listed here as a winter-specific option, it highlights Archoil’s approach to keeping Duramax engines running reliably in cold climates by maintaining fuel system integrity and combustion efficiency.
Buying Guide: Key Purchase Considerations
- Application goals: If you need injector cleaning and fuel system protection, choose products marketed as 6-in-1 or with explicit injector-cleaning benefits. For cold-weather Duramax use, prioritize anti-gel formulations with cetane boosts and water demulsification.
- Volume and economy: For regular maintenance on a Duramax, consider larger bottles or multi-pack options to cover more gallons per treatment and reduce refills.
- Post-combustion care: Some formulations target post-combustion cleaning (turbo, DPF); these are beneficial for engines with performance concerns or higher mileage, as they help reduce regeneration frequency.
- Fuel compatibility: Ensure the product explicitly states compatibility with modern diesel fuels and common rail systems used in Duramax engines.
- Winter performance: If you operate in cold climates, winter-defense or anti-gel variants can help prevent fuel gelation and improve cold starts, which is crucial for daily reliability.
- Maintenance strategy: Use products as part of a regular fueling routine rather than as a fix for already failing components. Pair additives with standard maintenance like oil changes and air filter checks for optimal results.
- Warranty and vehicle guidelines: Check your Duramax’s manual and warranty terms; some effects of additives may vary by model year or emission-control setup.
These selections provide a spectrum from cetane boosting and injector cleaning to anti-gel protection. When choosing, align the product’s primary benefits with your Duramax’s typical driving conditions, mileage, and climate, ensuring the additive complements your maintenance plan rather than replacing it.